Endocrine Abstracts

Introduction: Psoriasis is a chronic skin disease with a prevalence of 0.6 to 4.8%. Among the possible treatments, we highlight topic corticosteroids that can cause not only different local side effects (skin fragility and atrophy, striae, purpura, acne, telangiectasia, hypertrichosis) but also systemic side effects, including diabetes mellitus (DM), hypertension (HT), Cushing’s syndrome and hypothalamic–pituitary–adrenal (HHA) axis suppression.<p class="abs...

Background: Sézary syndrome (SS) is a more aggressive leukemic variant of cutaneous T-cell lymphoma (CTCL). Bexarotene (Targretin) is a synthetic rexinoid analogue designed for the treatment of advanced stages of cutaneous manifestations of CTLC. Bexarotene selectively suppresses thyrotropin secretion and up to 40% of patients develop reversible idiopatic central hypothyroidism. Severe mixed dyslipidemia may be present in up to 70%.Case report: Seve...

Introduction: The highly active antiretroviral therapy (HAART) completely changed the natural history and body composition of the infected patients. The lipodystrophy syndrome of HIV-infected patients (IP) is characterized by fat mass redistribution in the limbs, face lipoatrophy and abdominal lipohypertrophy. Dual-energy x-ray absorptiometry scan (DEXA) and bioelectrical impedance (BIA) are techniques to determine body composition (BC).Aims: Evaluate th...